Most banknotes have traces of cocaine on them; this has been confirmed by studies done in several countries. In 1994, the U.S. 9th Circuit Court of Appeals determined that in Los Angeles, out of every four banknotes, on average more than three are tainted by cocaine or another illicit drug.
Additionally, paper money in other parts of the world show a similar drug contamination, and studies indicate that they might even serve as a vector of disease, though researchers disagree over how easily diseases are transmitted this way. Five dollar bills have the most cocaine on them. This is because five dollar bills are the most printed bills in the U.S.
In a study reported in Forensic Science International, A.J. Jenkins, at the Office of the Cuyahoga County Coroner (Cleveland, OH), the author reports the analysis of ten randomly collected one-dollar bills from five cities, and tested for cocaine, heroin, 6-acetylmorphine, morphine, codeine, methamphetamine, amphetamine and phencyclidine (PCP). Bills were then immersed in acetonitrile for two hours prior to extraction and subjected to Gas chromatography-mass spectrometry (GC-MS) analysis. Results demonstrated that “92% of the bills were positive for cocaine with a mean amount of 28.75+/-139.07 micrograms per bill, a median of 1.37 μg per bill, and a range of 0.01-922.72 μg per bill. Heroin was detected in seven bills in amounts ranging from 0.03 to 168.5 μg per bill: 6-AM and morphine were detected in three bills; methamphetamine and amphetamine in three and one bills, respectively, and PCP was detected in two bills in amounts of 0.78 and 1.87 μg per bill. Codeine was not detected in any of the one-dollar bills analyzed”. The study confirmed that although paper currency was most often contaminated with cocaine, other drugs of abuse may also be detected in bills.